ADAPALENE GEL 0.1%
This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.
- Severe Acne On Face
- Severe Acne On Chest
- Severe Acne On Back
Adapalene is a retinoid-like compound for the treatment of acne vulgaris. It is a naphthoic derivative with a methoxyphenyl adamantyl side chain. Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization, and inflammatory processes all of which represent important features in the pathology of acne vulgaris.
Adapalene binds to specific retinoic acid nuclear receptors but does not bind to the cytosolic receptor protein. It has been suggested that topical adapalene may normalize the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.
Analysis of cryosections, radioactive tracing and fluorescence studies in excised human skin have shown that adapalene gel penetrates into the epidermis and dermis (especially the pilosebaceous units).
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