DYMISTA NASAL SPRAY SUSPENSION

Dymista Nasal Spray is used to relieve symptoms of allergic rhinitis such as runny or blocked nose, sneezing or itchiness when use of over the counter steroid nasal sprays or antihistamine nasal sprays alone are not considered sufficient.

What is Allergic Rhinitis?

Allergic rhinitis is inflammation of the lining of the nose provoked by an allergen such as pollen, dust, mould or the skin flakes of certain animals.

In susceptible individuals, when the cells lining the nose are exposed to certain allergens, histamine is released causing swelling, irritation and inflammation. This causes symptoms such as sneezing, itchiness and blocked or runny nose.

Allergens can vary between individuals but common triggers include pollen, dust, mould or animal skin flakes. The symptoms usually start fairly soon after being exposed to the allergen.

Some people experience symptoms all year round and others may be sensitive to seasonal allergens such as pollen and only experience symptoms for a few weeks at a time.

What is Dymista Nasal Spray?

Dymista nasal spray contains two active ingredients called azelastine and fluticasone propionate. Azelastine is an anti-inflammatory with significant antihistamine and stabilizing properties.

When administered to the nasal passage a relief of nasal allergic symptoms is seen within 15 minutes.

Fluticasone propionate is a corticosteroid with potent anti-inflammatory action which can take between 7-14 days for full effects. These two ingredients work together to reduce the symptoms of allergic rhinitis.

1 bottle should produce at least 120 sprays and is suitable for long term use to prevent symptoms of perennial and seasonal rhinitis.

How to use Dymista Spray?

You should always take this medicine at the dosage recommended by your doctor or pharmacist.

For adults aged 18 years and over: One spray in each nostril morning and evening. This medicine is suitable for regular long term use if required for seasonal or perennial symptoms.

1. Shake the bottle gently for 5 seconds by tilting it upwards and downwards and then remove the protective cap
2. Blow your nose to clear your nostrils
3. Keep your head tilted downwards towards your toes. Do not tilt head backwards
4. Hold the bottle upright and carefully insert the spray tip into one nostril
5. Close other nostril with your finger, rapidly press down once and sniff gently at the same time
6. Breathe out through your mouth
7. Repeat in other nostril

This product is intended for intranasal use only.

Once opened, use within 6 months.

Contains:

One actuation delivers 137 micrograms of azelastine hydrochloride (=125 micrograms of azelastine) and 50 micrograms of fluticasone propionate.

Product Warnings

Who should not use Dymista

This medicine should not be used by the following groups of patients without first seeking medical advice from your GP or our Pharmacist:

• If you are allergic to azelastine hydrochloride or fluticasone propionate or any of the other ingredients of this medicine
• You suffer from impaired adrenal function
• You have a change in vision or a history of increased ocular pressure, glaucoma and/or cataracts.
• You have tuberculosis or an untreated infection
• You suffer from a severe liver disease. Your risk of suffering from systemic side effects is increased.

Dymista is not suitable if you use any of the following medicines without first speaking with your GP or Pharmacist for medical advice:

• ritonavir
• cobicistat
• ketoconazole

If you have any questions about how this product may interact with your current medicines or conditions please contact us and one of our pharmacists will be more than happy to help.

What side effects could I expect?

Dymista Steroid Nasal Spray is generally well tolerated but the following side effects tend to be the most common:

• Nose bleeds
• Headache
• Unpleasant taste
• Unpleasant smell

This list is not exhaustive and for less common side effects please refer to the patient information leaflet.

Can I use Dymista if I am Pregnant or Breastfeeding?

This medicine is not suitable for patients who are pregnant or breastfeeding when purchased through our prescriber. Please speak with your GP or Midwife for further information.

Useful Information

This product is a medicine, and the sales are monitored to ensure the safety of our customers. From time to time we may impose limits on the amounts you may purchase and apply restrictions to the frequency of orders.

Store all medicines out of sight and reach of children and below 25c in a dry place away from direct sunlight.

Do not refrigerate or freeze. Shake gently before use.

Once opened, use within 6 months.

Please read the included leaflet carefully before using this product and if you have any questions please contact one of our pharmacists for more information.

Please contact your GP if appropriate regarding this product.